Yes. There are two options:
1. An infrared remote control (IR). For this, however, an infrared receiver must be connected to the WLED controller. Recommended types are TSOP38238 or KY-022. These receivers each have three pins: 3.3V, GND and IR data. IR data pin must be connected to a free GPIO pin. This GPIO must then be set as IR GPIO under "Config->LED Preferences". You also have to choose which infrared remote control you have. The following types are available: 24-key RGB, 24-key with CT, 40-key blue, 44-key RGB, 21-key RGB, 6-key black, 9-key red, JSON remote. The last type gives the opportunity to use any remote control. For this, the IR codes must be listed in a JSON file and then uploaded to the WLED.

2. Since WLED version 14.0-beta3: An ESP-NOW compatible remote control that uses radio network. An example of this is the „WIZmote“ remote control. This is based on an ESP microcontroller. ESP-NOW can be activated in WLED settings. You have to enter the Hardware MAC address of the remote control. This is determined by clicking on any button on the remote control and copying the last received MAC address from the "Last Seen" field to the "Hardware MAC" field in WLED ESP-NOW settings (“Config->WiFi Setup”) and saving it with "Save". Advantages: no special receiver needs to be attached to the WLED controller and the signals are transmitted via radio network. Therefore there is no line of sight between the remote control and the WLED controller required, as is the case with an IR remote control.

The 4 buttons "1"-"4" of the WIZmote remote control are linked to presets 1 to 4. The meaning of other keys is self-explanatory. Attention: WIZmote needs two good quality AAA batteries to work properly. If the batteries are too weak, the correct signal will not be sent, even if the blue LED on the remote control lights up briefly, actually indicating signal transmission.